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Published on Feb 4, 2021
Pediatrics
24. Kawasaki Disease
24. Kawasaki Disease

It affects children under the age of 6 years old with severe disease often associated with children under 1 year old.

Diagnostic criteria:. 5-day fever PLUS four of the following… ➔ Bilateral conjunctivitis ➔ Cervical lymph node >1.5cm ➔ Polymorphous exanthem ➔ Cracked lips/strawberry tongue ➔ Erythema/oedema/peeling of the hands/feet Other features include BCG scar inflammation, raised CRP, thrombocytosis and irritability without CNS infection. Beware:. diagnosis can be made before Day 5 of fever if clinical signs suggestive. Also if just 2-3 criteria present, consider incomplete Kawasaki.

Complications include:. ● Coronary aneurysms (causing thrombosis, MI and tamponade) ● Myocarditis ● Bleeding (due to aspirin) 

Consider echo EARLY in diagnosis

Treatment is with high-dose aspirin, IV immunoglobulin & Proton Pump Inhibitors.